7. Ghost of Lady Comstock, from BioShock Infinite

Who you gonna call? (Image from BioshockWikia)

Who knew fighting a ghost could be so freakin’ hard?

Lady Comstock, as the wife of Zachary Hale Comstock, was the First Lady of Columbia. Devoted to her husband, she spread his teachings to the citizens of the floating city. She gradually lost faith in him, however, after witnessing his cruelty to those who dared question him. When she threatened to publicly disclose the truth about their daughter Elizabeth, Zachary Comstock had her killed, then framed the rebel Daisy Fitzroy for the murder.

She returns during the events of BioShock: Infinite as a Siren – a specter capable of resurrecting dead enemies. What this means is that you’ll be consistently surrounded by armies of bad guys you’ve already killed, forcing you to keep moving and shooting lest you’re overwhelmed. Requires the patience of a saint to defeat.

She lights up like a Christmas tree! (Image from GamePressure)

An altar to the departed Lady Comstock (Image from HowManyPrincesses)