15. Deathclaw Gauntlet Found During “The Devil’s Due” Quest

“Uh excuse me? You just punched a hole in my chest?”

Constructed out of two deathclaw finger bones, this power fist packs a seriously mean punch. I’m talking rude.

There are actually a few different ways to get a hold of this menacing claw. If you want one right away, head to the Museum of Witchcraft to start “The Devil’s Due” quest. When returning the egg to the deathclaw nest, this little guy will be there.

Deathclaw Gauntlet deals 25 damage and costs 40 AP. It slashes at medium speed, weighs 10, and has a value of 75.

14. Lorenzo’s Artifact Gun Awarded for “The Secret of Cabot House” Quest

In the name of science, anything goes.

The mod making this gamma gun unique can be removed and added to other weapons of its type. Installing it gives each bullet a knockback effect that stuns enemies with far greater impact than a normal gamma gun. Just talk to Jack Cabot in Cabot House and complete his quest to get this far out device of science.  

Lorenzo’s Artifact Gun deals 25 damage and 10 radiation damage. It has 66 fire rate, 203 range, 69 accuracy, a weight of 4.5, and a value of 752.

13. Experiment 18-A Sold by the Synth Requisition Officer

Time to guinea pig this bad boy.

This automatic plasma rifle comes with 25% more fire rate and 15% faster reload. Once you reach the illusive Institute, you can purchase this weapon for yourself.

Experiment 18-A deals 56 damage and has 136 fire rate, 206 range, 140 accuracy, a weight of 6.6, and a value of 1,809.

12. Partystarter Sold by KL-E-0

“I don’t start parties. I finish them.”

Are you an assassin who’s tired of the same old, same old? Sniper rifles, silenced pistols, and combat knives getting dull? Well look no further than this missile launcher, complete with a night scope and 50% bonus damage against humans!

Believe me when I say they’ll never see it coming.

Partystarter deals 150 damage, weighs 21, and is valued at 314.

11. Syringer Sold by Doctor Sun

If I was a cheesy Saturday morning cartoon villain, I’d say, “It’s time for your shots!”

Do you consider yourself a mad scientist? If so, this rifle was made for you. It uses syringes as ammo, which you can construct at a chemistry station for varying effects. Ever wanted to see a bloatfly burst from a raider’s chest Alien style?

Me neither. But now you can!

Syringer deals damage based on the type of syringe loaded up. Its exact stats depend on the mods it spawns with.